Seleccionar página
Fertility clinic in Spain

In Vitro Fertilization (IVF) with ICSI in Madrid, Spain

In vitro fertilization (known by its acronym IVF) is the union of a woman’s egg and a man’s sperm in a laboratory. ‘In vitro’ means that it is beyond the body, outside of it. On the other hand, ‘fertilization’ means that the sperm has already fixed and has entered the egg, creating the embryo.

Arpa Médica Fertility Clinic in Madrid is one of the leading centers of reproductive medicine in Spain. In fact, it is one of the most well-known clinics in the medical specialty of Assisted Reproduction and Fertility treatments of the country. Nonetheless, we receive patients from all over Europe, America, the Middle East and Africa, every year.

The staff of our medical center can speak several languages as English, German, French, and Italian. Thanks to this, patients of the clinic feel comfortable, since all the relevant information is provided in a preferred language. Many couples with reproductive problems or women who decide to postpone their pregnancy or be single mothers have seen their mother and father dream come true thanks to our professionals.

What is In Vitro Fertilization (IVF)?

IVF is a treatment that has helped many women in their desire to become mothers. IVF consists of the union of male (sperm) and female (oocyte) gametes in order to create embryos that will later be transferred to your uterus using the embryo transfer technique.

For whom is In Vitro Fertilization indicated?

In vitro fertilization is an alternative treatment when other fertility treatments have previously failed and in patients with disorders such as, among others:

  • Absence, obstruction or injury to the tubes.
  • Decrease in the number and / or mobility of spermatozoa or increase in morphological alterations of the same.
  • Moderate or severe endometriosis.
  • Ovulation disorders.
  • Failures of other treatments (programmed intercourse, artificial insemination).
  • Advanced age.



In Vitro Fertilization treatments in Madrid with prices adapted to the current social situation with the Covid-19 pandemic so that dreams of motherhood and fatherhood are not delayed or even canceled.

Start now to fulfill your dream!

Ask about our diagnostic pack through the free reservation, you will have the necessary tests.

IVF PRICE € 3,500 (Free reservation)

In vitro fertilization is an alternative treatment with a higher success rate when other fertility treatments have previously failed.

Make an appointment. Free first evaluation at a Madrid clinic.

Atención personalizada de la Asesoría de Reproducción

Atención técnica de particulares de Embriología

Contacto vía WhatsApp


At Arpa Médica we use​ Embryoscope+

In this video recorded at our fertility clinic in Madrid, the development of three embryos is easily seen thanks to the Time-Lapse technology of the Embryoscope + that we use at Arpa Médica. By constantly monitoring the development of the embryo in images with this technology, we can easily choose the best embryo to transfer, considerably improving the pregnancy success rates.

Phases of In Vitro Fertilization

In vitro fertilization treatment consists of different phases

1. Menstruation

2. Ovarian stimulation

In the natural process of a female menstrual cycle, women produce a single oocyte (ovum) each month. Through the administration of medication, what we seek in this first phase of In Vitro Fertilization is to stimulate the ovary and induce the production of more oocytes. If the creation of many oocytes is achieved, the possibility of gestation is greater since more embryos can be obtained. We monitor the evolution of this process through periodic ultrasound checks, and sometimes blood tests.

3. Embryo culture and in vitro fertilization

Once the oocytes have been extracted by puncture, and already with your partner’s sperm, the oocytes are fertilized in the laboratory using two techniques: conventional IVF or intracytoplasmic sperm injection (ICSI)

Post-embryo transfer process

About two weeks after the embryo transfer, the pregnancy test is performed. Two possibilities are contemplated after embryo transfer:

  • 1. You get pregnant

    The In Vitro Fertilization treatment has been successfully completed. From this moment, we discharge you and you continue with a gynecological monitoring of the pregnancy that can be, if you want, with our obstetric team, to continue with a personalized treatment.

  • 2. You don’t get pregnant
    When the cycle does not end with pregnancy, the most important thing is not to lose hope and stay calm. That you do not get pregnant in the first cycle of In Vitro Fertilization does not mean that you cannot do it in subsequent cycles. The two options before this possibility are:

a. If you have frozen embryos, we perform a cryotransfer, that is, the embryos that have been cryopreserved are transferred to your uterus as in the first cycle of IVF. It should be mentioned that preparing the uterus for a frozen embryo transfer is much easier, since it is not necessary to repeat the process of ovarian stimulation and follicular puncture.
b. If you do not have frozen embryos, we carry out a second attempt or second cycle, starting the In Vitro Fertilization process from scratch.

4. Follicular puncture

When it is verified by ultrasound means that the follicles have reached the appropriate diameter and number, the follicular puncture is programmed. Approximately 36 hours before the puncture, an injection of the hormone hCG should be administered, which induces oocyte maturation in a similar way to how it occurs in the natural cycle. The ovarian or follicular puncture consists of the extraction of the follicular fluid found in the oocytes by means of a surgical intervention that is carried out in the operating room, by means of sedation and whose duration does not usually exceed 15 minutes. Although it is not usual, if after the puncture you feel any discomfort, you can call the clinic to be informed of what steps to follow.

5. Embryo transfer

The embryo transfer is the last and decisive step in the process to achieve your pregnancy through In Vitro Fertilization. It is a crucial phase of treatment.
The process is very simple although, like the puncture, it is carried out in the operating room. The placement of the embryos is carried out with a specific catheter, made with a very flexible material, so as not to damage the walls of the uterine cavity, and you do not need to be sedated as it is not a painful process.

After the embryo transfer, you remain at rest for about half an hour. Then you can resume your daily activity, always in moderation. The embryos left over from the process will be frozen, in order not to repeat the process of ovarian stimulation and follicular puncture again, in the event that you do not get pregnant in the first cycle of in vitro fertilization.

6. Test to see if there is pregnancy

How many cycles can you do?

At Arpa Médica we will guide you in the most appropriate way to perform the following treatment. We will assess how the first cycle went and if the assessment is correct then we will advise you to repeat the In Vitro Fertilization cycle.


‘We love what we do’

More information about Fertility and Assisted Reproduction treatments in our Madrid clinics:

Propósito del Grupo Arpa Médica

Arpa Médica works with Merck. The best guarantee of quality and innovation to help our patients’ dream of being parents.


Our Professionals

Click on his image to show the curriculum vitae

CMO, Ginecólogo, Obstetra y Fertilidad

Dr. Ignacio Palomo

Ginecólogo, Obstetra y Fertilidad

Nº de Colegiado:

Más información en


Médico Fertilidad

Dra. Martha Luna

Médico especialista en Fertilidad

Nº de Colegiado:

Más información en

Embriólogo Senior

Luis González Viejo

Embriólogo Senior

N.º de Colegiado: 18.898-M

Más información en



Alejandra Boix


N.º de Colegiado: 20.429-M

Más información en

Nutricionista y Dietista

Dra. Irene Santacruz

Nutricionista y Dietista

Nº de Colegiado: MAD-00.462

Más información:

Para más información

Contacta con Nosotros

La vida es el arte del encuentro. Deseamos formar parte de tu camino para ayudarte a recorrerlo con la mejor calidad de vida.

Abrir chat
👨🏻‍⚕️ ¿Necesitas ayuda?
👨🏻‍⚕️¡Bienvenido a Arpa Médica! Si tienes cualquier duda puedes preguntarnos en nuestro Whatsapp.
Pide Cita Online